Thursday, March 28, 2019

Dendritic Spine Pathology in a Schizophrenia-related Neurodevelopmental Model


Conference name: 2nd International conference on pathology
Short name: Pathology 2019
Venue : Paris,France | July 5-6,2019
URL: https://bit.ly/2GS09CI


Schizophrenia is a neurodevelopmental disorder identified by psychotic episodes, as well as cognitive deficits. There are reports of multiple alterations in the brain in schizophrenia, such as fewer dendritic spines with shape abnormalities in cortical and subcortical areas. A correlation has been established between shape and function in dendritic spines; and as the main site of excitatory synapses, the dendritic spine pathology represents a potential target for novel therapeutic tools in schizophrenia. 

Author:Gonzalo floris and friends

Neonatal ventral hippocampus lesion (nVHL) in the rat has been extensively used to examine some of the pathophysiological mechanisms of schizophrenia since it mimics several behaviors, as well as abnormalities in morphological corticolimbic neurons. Thus, in this report, we determined the effects of the nVHL on locomotor behavior and memory in postpubertal rats.


To know more about Pathology and its Applications do attend International Conference on Pathology 2019 http://pathology.alliedacademies.com/

Contact
KRISTIE NOVA
Program Director | PATHOLOGY 2019
Phone: (44) 20 3769 1755
Email: pathology(at)alliedannualsummit(dot)com

No comments:

Post a Comment