Conference name: 2nd International conference
on pathology
Short name: Pathology 2019
Venue : Paris,France| July 5-6,2019
URL: https://bit.ly/2GS09CI
The link between pancreatic intraepithelial neoplasia (PanIN), one of the major precursor lesions of pancreatic ductal adenocarcinoma (PDAC), and epithelial-to-mesenchymal transition (EMT). Immunohistochemically, they searched for possible regulators of EMT. They analyzed expressions of SNAIL, SLUG, TWIST1, and ZEB1 in high-grade PanIN (HG-PanIN) and PDAC. Overall, 71 PDAC patients with surgically resected specimens were included. A significantly better relapse-free survival (median survival time [MST] of 11.3 months vs 4.4 months) and overall survival (MST of 25.2 months vs 13.6 months) was observed in PDAC accompanied by SNAIL-positive HG-PanIN. Overall, a possible significant role of EMT in the development of PDAC from HG-PanIN was suggested. A distinct subgroup with a better prognosis could be predicted by SNAIL.
Author: Fujiwara S
To know more about Pathology and its Applications do attend
International Conference on Pathology 2019 http://pathology.alliedacademies.com/
Contact
KRISTIE NOVA
Program Director | PATHOLOGY 2019
Phone: (44) 20 3769 1755
Email: pathology(at)alliedannualsummit(dot)com
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